Her sister, Harmony, said she was "in a hard place" when she went missing and she wanted her to know that "there is endless love out there" and they are searching for her.
Frank was last seen leaving her brother's home on Buffalo's West Side on Monday where she was visiting for the holidays.
Frank is 5'5" tall and 150 pounds with short, graying blonde hair. She was wearing a green canvas coat and black-rimmed glasses. She took her wallet, but left her cell phone behind.
There will be a search party on Sunday and they are asking for volunteers for a windshield search in Allentown and the West Side area and also to post flyers.
If you have any information as to Frank's whereabouts, please call 716-863-6906 or leave an anonymous tip here.